The Malignant Carcinoid Syndrome

Anesthesia and the malignant carcinoid syndrome.

MDCT imaging in malignant carcinoid syndrome.

A 65-year-old lady presented with sudden onset of palpitations, headache, perspirations and flushing. Clinical examination revealed tenderness in right lumbar region. Ultrasound abdomen revealed multiple hyperechoic hepatic lesions and a mesenteric mass. Contrast-enhanced computerized tomography (CECT) abdomen revealed multiple hypervascular hepatic lesions. Two enhancing mesenteric masses with...

Carcinoid syndrome due to a malignant somatostatinoma.

Somatostatinoma is one of the rarest tumours of the endocrine pancreas. Cardinal manifestations of a somatostatinoma include gallstones, mild diabetes mellitus, steatorrhoea, diarrhoea and dyspepsia. Like any other pancreatic islet cell carcinoma, a somatostatinoma may also produce several different hormones such as adrenocorticotropic hormone, calcitonin, vasoactive intestinal polypeptide, pan...

Observations on a patient with the malignant carcinoid syndrome.

The syndrome of malignant carcinoid tumour with excessive production of 5-hydroxytryptamine (5-HT, serotonin, enteramine) is currently of great interest (Mattingly, 1956; MacDonald, 1956; Ritchie, 1956; Thorson, 1958). As well as reporting clinical, pharmacological, and necropsy data from a typical case, this paper describes for the first time changes inthepulmonaryvasculature that may be relev...

A Case of Carcinoid Syndrome Due to Malignant Metastatic Carcinoid Tumor with Carcinoid Heart Disease Involving Four Cardiac Valves

BACKGROUND Carcinoid tumor, benign, low-grade malignant, and high-grade malignant, can be associated with the release of vasoactive substances that cause symptoms including cutaneous flushing, diarrhea, and bronchospasm. In 50-60% of patients with carcinoid syndrome, the vasoactive substances cause fibrosis of the pulmonary and tricuspid heart valves which lead to regurgitation and right-sided ...